Abstract Purpose The research endeavors to explore the implications of CD47 in cancer immunotherapy effectiveness.Specifically, there is a gap in comprehending the influence of CD47 on the tumor immune microenvironment, particularly in relation to CD8 + T cells.Our study aims to elucidate the prognostic and immunological relevance of CD47 to enhanc
PRECISE LASER-BASED OPTICAL 3D MEASUREMENT OF WELDING SEAMS UNDER WATER
This paper deals PSORIASIS CONDITIONER with the development of a measuring procedure and an experimental set-up (stereo camera system in combination with a projecting line laser and a positioning unit) which are intended to detect the surface topography, particularly of welds, with high accuracy in underwater environments.The system concept makes p
Genome Comparisons of Candida glabrata Serial Clinical Isolates Reveal Patterns of Genetic Variation in Infecting Clonal Populations
Candida glabrata is an opportunistic fungal pathogen that currently ranks as the second most common cause of candidiasis.Although the mechanisms underlying virulence and drug resistance in C.glabrata are now starting to be elucidated, we still lack a good understanding of how this yeast adapts during the course of an infection.Outstanding questions
Plectin in Skin Fragility Disorders
Plectin is a multi-faceted, 500 kDa-large protein, which due to its expression in different isoforms and distinct organs acts diversely as a cytoskeletal crosslinker and signaling scaffold.It functions as a mediator of keratinocyte mechanical Scarves stability in the skin, primarily through linking intermediate filaments to hemidesmosomes.Skin frag